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Similarly to the chemokine CCL the level
2020-04-03
Similarly to the chemokine CCL-5, the level of the chemokine SDF-1 in the groups of individuals with APD did not differ from its level in the control group. However, a slight increase in the level of this chemokine was recorded in the group of women and men with APD and PTSD as compared with the cor
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Minocycline HCl More recently evidence suggests that dysregu
2020-04-03
More recently, evidence suggests that dysregulation of CRF signaling may also be implicated in panic disorder. For instance, polymorphisms in the CRF1, but not CRF2, gene have been associated with susceptibility to panic disorder in German and Japanese population samples (Ishitobi et al., 2012, Keck
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br COTSget based Architectures This section describes
2020-04-03
COTSget-based Architectures This section describes how our COTSget-based architectures are defined. We use a design inspired by MDE to build a Domain-Specific Language (DSL) of the architecture, as can be seen in the metamodel of Fig. 3. This metamodel defines the abstract syntax of our DSL and i
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lamotrigine sale The need for dedicated DAPT updates is well
2020-04-03
The need for dedicated DAPT updates is well justified by the large amount of data and new information generated in the field over the past few years. As expected, the ACC/AHA and ESC updates contain large areas of overlap as well as some differences. Differences were largely explained by the differe
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Introduction Primitive neuroectodermal tumors PNETs are mali
2020-04-03
Introduction Primitive neuroectodermal tumors (PNETs) are malignant, small round cell tumors of neural crest origin which typically arises from bone or soft tissue in the trunk/axial skeleton/paraspinal regions in adolescents and young adults and comprises of 50% cases with local recurrence and met
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br Introduction O Methylguanine DNA methyltransferase MGMT i
2020-04-03
Introduction O6-Methylguanine-DNA methyltransferase (MGMT) is a DNA-repair enzyme that specifically transfers alkyl adducts from the O6 position of guanine to the cysteine residue (Cys145) in its active site. In cancer cells, this ability of MGMT disrupts the cytotoxic actions of alkylating antic
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Neuropsychological studies of adults with
2020-04-02
Neuropsychological studies of adults with problem gambling indicate impairments in many cognitive areas including inhibition, working memory, decision-making, cognitive flexibility, and executive planning (Ledgerwood et al., 2012, Goudriaan et al., 2006). Dopamine is a neurotransmitter that regulate
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Simon discusses this in the remarks
2020-04-02
Simon discusses this in the remarks and historical notes section following the general discussion of dynamically defined Verblunsky coefficients; see [12, pp. 706–707]. He points out that “understanding almost periodic Verblunsky coefficients is an intriguing open area” and in particular describes w
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br Materials and methods br Results br Discussion
2020-04-02
Materials and methods Results Discussion One novel finding in our study is that CK2 inhibition preserved axon function and structure in WM against ischemia. Consistent with these findings, oligodendrocytes, astrocytes, myelin, and casin were found to express CK2α. The robust expression pat
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The acetylcholinesterasic activity of exposed animals after
2020-04-02
The acetylcholinesterasic activity of exposed animals, after treatment with diverse concentrations of uranium and following distinct recovery periods, remained unaltered for all species. This finding suggests that uranium, in spite of being a water-soluble metal, does not exert any effect on the sel
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br Conflict of interest br
2020-04-02
Conflict of interest Acknowledgements This study was supported by the National Natural Science Foundation of China (No.31571839), the Chinese Ministry Program for New Century Excellent Talents in University (NCET-12-0865), and Special Fund for Agro-scientific Research in the Public Interest (N
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Prostanoids typically act in an
2020-04-02
Prostanoids typically act in an autocrine and paracrine fashion by binding to specific receptors in target selective androgen receptor modulators and there is evidence that both PGE2 and prostacyclin may be required for the optimal activation of angiogenesis (Hata and Breyer, 2004). PGE2 and prosta
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In pregnancy maternal uterine spiral artery SA remodeling is
2020-04-02
In pregnancy, maternal uterine spiral artery (SA) remodeling is essential for ensuring efficient blood flow to the developing fetus. A subset of CD49a+Eomes+ decidual NK WAY-100635 maleate salt sale (dNK) that actively secretes GFs, such as pleiotrophin and osteoglycin, have recently been described
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br The classical ubiquitination pathway Ubiquitination is an
2020-04-02
The classical ubiquitination pathway Ubiquitination is an enzymatic process that involves the addition of an ubiquitin protein to a substrate that usually becomes inactivated followed by degradation in the proteasome; however, several other functions have also been described. For the discovery of
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br Introduction O Methylguanine DNA methyltransferase
2020-04-02
Introduction O6-Methylguanine-DNA methyltransferase (MGMT) is a DNA-repair enzyme that specifically transfers alkyl adducts from the O6 position of guanine to the cysteine residue (Cys145) in its active site. In cancer cells, this ability of MGMT disrupts the cytotoxic actions of alkylating antic
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