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br Using the same sort of methods
2021-06-18

Using the same sort of methods, we can also address the proof of Theorem 1.2. The first part of the proof is made much easier if we use the “sieving” construction. Concretely, given a CMV operator , let denote the CMV operator with This induces a simple change in the spectrum; namely, if denotes
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Analysis of DNA fragmentation We followed
2021-06-18

Analysis of DNA fragmentation. We followed a modified Hirt extraction procedure for analysis of DNA fragmentation. Cells were suspended in TNE buffer (1M NaCl, 20mM Tris–HCl, pH 7.4, 2mM EDTA, and 0.6% SDS) at a density of 106 cells/ml and incubated overnight on ice. The next day, cellular debris wa
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br Introduction The cervix is a poorly studied component
2021-06-18

Introduction The 4-iodo-SAHA synthesis is a poorly studied component of the mare’s reproductive tract. It has anatomical and biological defense mechanisms involved in the delicate balance between immunological tolerance, sperm transport and biological defense. Anatomically, the cervix is compose
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River sand was graded in accordance with ASTM C
2021-06-18

River sand was graded in accordance with ASTM C778 [47] (see Table 2). The graded sand had a water formyl of 1.00%, fineness modulus of 3.49 and specific gravity of 2350kg/m3. A polycarboxylate based superplasticizer called ZP with pH of 7±1 and specific gravity of 1.1±0.02 was also used to adjust
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Since the dideoxy analogues and served as
2021-06-18

Since the 1,2-dideoxy analogues, and , served as substrates for TgTCEA and TgTCEB, respectively, with the higher affinity (lower ) and lower turnover number (lower ) than their authentic substrates, PosA and PosB (such trend was more evident on analogue for TgTCEB than on analog for TgTCEA), an intr
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br Results br Discussion Many studies have
2021-06-18

Results Discussion Many studies have shown that intrinsic properties of the E2 enzyme govern the nature of the Ub modification, including both the multiplicity of the Ub modification and the specific Syringin type in the case of polyubiquitin chains [3], [4], [9], [14]. Whereas previous studi
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br Development of the double strand break repair model
2021-06-18

Development of the double strand break repair model for meiotic recombination Meiotic recombination was first described by Frans Alfons Janssens using THZ1 Hydrochloride in the salamander Batracoseps attenuatus in 1909 [21] and then further elaborated at the genetic level in Drosophila by Thomas
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To examine the influence of aromatic motifs on the bridging
2021-06-18

To examine the influence of aromatic motifs on the bridging lysine esters we analysed DNA alkylating activity of the set of compounds 1–6. The lysine derivatives were chosen as it is relatively easy to prepare different esters and thereby study the impact of different groups on the reactivity toward
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The role of ARA cyp metabolites in the liver
2021-06-17

The role of ARA-cyp450 metabolites in the liver is still unclear [44]. However, ARA-cyp450 genes metabolize other fatty acids such lauric and palmitic CI-1040 [45]. It was found that decreased cyp4a expression caused fatty livers through reduction of fatty acid metabolism [46]. In this study, we fo
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The early serologic response of infants to
2021-06-17

The early serologic response of infants to infection with HIV-1 is obscured by the presence of transplacentally acquired maternal HIV antibody. However, the HIV EPI-001 produced in vitro by peripheral blood from infants has been studied (Pollack et al., 1993) and it has been shown that neonatal inf
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These evidence prompted us to investigate
2021-06-17

These evidence prompted us to investigate the effectiveness of CT-133, a newly discovered, well-tolerated, selective and potent CRTH2 antagonist, as a treatment of ALI. CT-133 has shown a potential response in treating chronic obstructive pulmonary disease (COPD), allergic rhinitis and mg molecular
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TCS JNK 5a br Disclosures br Introduction The presence of an
2021-06-17

Disclosures Introduction The presence of anti-viral T-cell immunity is crucial for effective and sustained protection against Cytomegalovirus (CMV) following allogeneic stem cell transplantation (alloSCT) [1]. In vitro and in vivo T-cell depletion (TCD) via addition of the anti-CD52 monoclonal
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Finally considering the encouraging inhibitory and selectivi
2021-06-17

Finally, considering the encouraging inhibitory and selectivity properties of compound and against isolated CK1δ, we have also acquired a very preliminary cytotoxicity profile on human ovarian carcinoma cell line (2008) and on its cisplatin-resistant clone (C13). Results showed that after 48h of exp
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br Conflict of interest br Acknowledgements This
2021-06-17

Conflict of interest Acknowledgements This work was partially supported by University of Cagliari. Introduction Organophosphorous pesticides (OPs) are wildly used in the world due to high efficiency, broad spectrum and low residue, which in turn results in environmental pollution and adver
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br Loss of Chk sensitizes cells to
2021-06-17

Loss of Chk 1 sensitizes DMH-1 to hypoxia/reoxygenation In contrast to Chk 2, studies have identified Chk 1 as being phosphorylated in an ATR-dependent manner at residue serine 345 during hypoxia [18]. More recently, siRNA mediated inhibition of Chk 1 signaling was found to sensitize cells expos
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