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Completion of h of education was significant in
2021-07-03
Completion of 150 h of education was significant in virtually all prior studies of the 150-h requirement (Allen and Woodland, 2006, Boone et al., 2006 and others). While the 150-h requirement applies to licensure, students are often permitted (as in California) to sit for the CPA exam with fewer tot
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These cognitive deficits may suggest that cognitive therapy
2021-07-03
These cognitive deficits may suggest that cognitive therapy and pharmacotherapy for gambling behavior may ultimately wish to consider genotyping as a means of better targeting treatment approaches. If core cognitive deficits are shown consistently in certain subgroups of gamblers based on genotype,
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Gastrointestinal tone can be effectively modulated by cholin
2021-07-03
Gastrointestinal tone can be effectively modulated by cholinesterase inhibitors. As parasympathetic fibers release Streptomycin sulfate mg to contract the circular and longitudinal intestinal muscles, AChE inhibition can facilitate those actions. Postoperative ileus (delayed gastric emptying after
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br Pathophysiology of premature ovarian failure By the age
2021-07-03
Pathophysiology of premature ovarian failure By the age of 40 years, 1% of women spontaneously develop POF [18]. The normal menopause occurs at an average age of 51 years [19] and results from ovarian follicle depletion [20], whereas POF is a heterogeneous disorder and can result from either foll
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Introduction Breast cancer is a
2021-07-03
Introduction Breast cancer is a highly prevalent malignancy. There are some recognized risk factors for breast cancer, like early menarche or late menopause, which increase the length of the exposure to hormones, as a result of a higher number of ovarian cycles [1]. Moreover, there is evidence supp
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Our previous high throughput screening HTS campaign using au
2021-07-03
Our previous high-throughput screening (HTS) campaign using automated, robust, and sensitive fluorescence based NSC 74859 assay [10], [11] led to the identification of several EPAC specific inhibitors (ESIs), and was subsequently followed by extensive hit-to-lead optimizations [20], [21], [22], [23
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br Chondroitin sulfate proteoglycans CSPGs are
2021-07-03
Chondroitin sulfate proteoglycans (CSPGs) are major components of the extracellular matrix in cartilage. Each CSPG comprises a single core protein and attached chondroitin sulfate (CS), belonging to the glycosaminoglycan family of sugar chains. CSPGs and CS are involved in numerous biological and
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In our opinion the precise function of AE
2021-07-03
In our opinion, the precise function of AE of S. mansoni (Sm32) remains unclear, and accurate knowledge of the three dimensional structure of this enzyme would be valuable for a better understanding the molecular basis of many of its properties, including its role in the host-parasite interaction, a
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The purpose of this study is to investigate KDM
2021-07-03
The purpose of this study is to investigate KDM1B expression and its functional significance in PC. We used lentivirus-mediated shRNA to down-regulate KDM1B expression in PC cell lines in vitro and detected the changes of cell proliferation and apoptosis. These studies provided a novel insight into
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br Conclusions Mulan is a mitochondrial E ubiquitin
2021-07-03
Conclusions Mulan is a mitochondrial E3 ubiquitin ligase with diverse roles in cell growth, cell death, and mitophagy. To better understand the mechanism of Mulan's function we used a modified yeast two-hybrid system to isolate proteins that interact with its cytoplasmic RING domain (amino acids
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br Results and Discussion br Experimental Procedures br
2021-07-03
Results and Discussion Experimental Procedures Acknowledgments The ubiquitin–proteasome system (UPS) is important for biological processes such as protein degradation and protein function regulation. In general, poly-ubiquitinated proteins are degraded by proteasomes, and some proteins ac
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Several DA receptors heteromers with a
2021-07-03
Several DA receptors heteromers with a therapeutic potential have been described, including D1R/D3R (Fiorentini et al., 2010), but their roles remain to be established. Moreover, most studies on receptor heteromers in addiction focused on the striatum because of its key role in the pathology and its
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Atipamezole hydrochloride Fig S an adrenoceptor antagonist i
2021-07-02
Atipamezole hydrochloride (Fig. S1), an α2-adrenoceptor antagonist, is commonly used by veterinarians to recover animals from sedation-anesthesia induced by α2-adrenoceptor agonists. Recent studies in animals suggest that atipamezole might have beneficial effects in PIK-III sale damage repair, it a
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br Acknowledgments br Introduction to the somatic
2021-07-02
Acknowledgments Introduction to the somatic mitotic cell cycle Cell cycle dysregulation and cancer Structures of the cyclin-dependent protein kinases Structure of the CDK hydrophobic skeletons Classification of protein kinase-drug complexes Dar and Shokat defined three Zafirlukast
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Future analysis could consider using
2021-07-02
Future analysis could consider using fixed effects also with the level set field, , in order to investigate which covariates explain the classification, a feature of the proposed model that we have not yet investigated. Further, multi-type point patterns may also be analyzed with the proposed model
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