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Princen Panier specifically address the issue of ACE
2024-06-20
Princen, 2012, Panier, 2013 specifically address the issue of ACE using the commercial database AMADEUS. However, both studies focus only on corporate leverage and the ACE in Belgium. Due to the lack of a counterfactual, these authors consider firms in other European countries, e.g., France, as a co
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Chronic inflammation is associated with both
2024-06-20
Chronic inflammation is associated with both initiation and progression of many neoplastic conditions [149], and ATX may be a player in the process. ATX/LPA signaling is positively correlated with the invasive and metastatic potential of several cancers including melanoma, breast cancer, ovarian can
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Aurora A overexpression is also related to the
2024-06-20
Aurora-A overexpression is also related to the activation of NF-κB, a potent anti-apoptotic effector that may play a role in preventing apoptosis in cancer RITA [18]. These data show that we are still at the beginning of unraveling the complex mechanism by which these gene products and proteins in
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MTT Previously using a P lacZ reporter gene
2024-06-20
Previously, using a P-lacZ reporter gene system, it has been shown that the β-galactosidase activity was 9-fold higher in the stationary phase MTT when compared with those of the exponential phase [15]. Furthermore, inositol supplementation did not have a major effect on the expression of β-galacto
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br Results br Discussion ER and GR play
2024-06-20
Results Discussion ER and GR play opposite phenotypic roles in the normal endometrium, with ER promoting growth and GR inhibiting growth. Here, we show that in endometrial cancer, GR expression is associated with worse outcomes and higher-grade tumors, and this association is observed only in
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APJ receptors have a amino
2024-06-19
APJ receptors have a 380 amino aa2414 sequence with a characteristic G-protein structure, including seven transmembrane domains and post-translation modification sites for phosphorylation, palmitoylation and glycosylation along with association sites for β-arrestin (O'Dowd et al., 1993). APJ recepto
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br Materials and methods br Results br Discussion
2024-06-19
Materials and methods Results Discussion Pulmonary fibrosis is a progressive and chronic lung disease and its typical features include mibefradil synthesis proliferation, epithelial injury, chronic interstitial inflammation, increased extracellular matrix (ECM) production, and collapse of
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br Conclusion br Introduction Breast
2024-06-19
Conclusion Introduction Breast cancer is the most common cancer and second leading cause of cancer-related deaths in women [1,2]. There were about 1.7 million new cases of breast cancer worldwide in 2012 [3], and the number of new cases of female breast cancer is expected to increase to 3.2 mi
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In spite of this unexpectedly after three
2024-06-19
In spite of this, unexpectedly, after three-week cherry puree consumption no AC increase was observed, irrespective of the method used (Table 2). A statistically significant decrease of AC was even measured by LOX-FL and ORAC methods (−3.5% and −9%, respectively). Nevertheless, a much more evident d
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Second the choice of the PAABD
2024-06-19
Second, the choice of the PAABD is critical for an efficient and sensitive biosensor. The sequence of the PAABD should present high affinity and efficient recognition of the phosphorylated substrate, as opposed to poor affinity for the unphosphorylated substrate, and should display a fully reversibl
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Thalidomide is now a well known antiangiogenic agent This pr
2024-06-19
Thalidomide is now a well known antiangiogenic agent. This property of thalidomide is being extensively researched upon, for its significant utility in the treatment of various malignant tumors. Studies show that thalidomide efficaciously inhibits various pro-angiogenic factors such as tumor necrosi
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Circular dichroism CD provides useful information about
2024-06-19
Circular dichroism (CD) provides useful information about protein structure, the extent and rate of structural changes and ligand binding. CD is a form of light Quinupristin-Dalfopristin Complex mesylate spectroscopy that measures differences in the absorbance of right- and left-circularly polarize
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Asparagine synthetase ASNS is a
2024-06-19
Asparagine synthetase (ASNS) is a glutamine amidotransferase that catalyzes ATP-dependent synthesis of asparagine and glutamate from aspartate and glutamine. Upregulation of ASNS expression renders leukemia cells resistant to l-asparaginase treatment, and ASNS is essential for cell survival in the a
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Many of the cellular processes regulated by AKT activation a
2024-06-19
Many of the cellular processes regulated by AKT activation are also controlled by other intracellular pathways such as the MAPK pathway, the PLCγ pathway, but also, directly or indirectly, by signaling pathways not linked to RTK transmembrane receptors, such as growth factor-linked signaling affecti
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In a recent series of studies from our laboratory
2024-06-19
In a recent series of studies from our laboratory, to characterize the contractile systems within the rat angiotensin 2 receptor blocker wall, three conditions were identified that led to detrusor activity: spontaneous micro-contractions, electrical field stimulated (EFS) contractions and muscarini
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