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guanylyl cyclase Roux en Y gastric bypass
2019-04-26
Roux-en-Y gastric bypass surgery is a common cause of malabsorption associated with hyperoxaluria in obese patients and those with malignancies. Postoperatively, patients may have steatorrhea, weight loss, and diarrhea, resulting in malabsorption syndrome, which would increase excessive intraluminal
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A decreasing trend in CRT D implantation has
2019-04-26
A decreasing trend in CRT-D implantation has been reported recently, based on the database from the National Inpatient Sample in the USA [20]. They found that advancing age and an increasing comorbidity burden were associated with a reduced likelihood of CRT-D, and speculated that the decline in CRT
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br Conflict of Interest br
2019-04-26
Conflict of Interest Acknowledgments Introduction Human ether-a-go-go-related gene (hERG) encodes the alpha subunit of the rapidly-activating delayed-rectifier K+ channel, which plays a pivotal role in repolarization of cardiac action potentials (APs) [1]. Most of mutant hERG proteins causi
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Sor Juana cuyo genio era para Vigil indudablemente antimonac
2019-04-26
Sor Juana, cuyo genio era para Vigil indudablemente “antimonacal” —recordemos que estamos en pleno periodo posterior resperidone las leyes de desamortización de los bienes eclesiásticos— tuvo que tomar una decisión “dictada por las exigencias de su sociedad”, por ello, continúa Vigil, si hubiese nac
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Uric acid level was high at presentation
2019-04-26
Uric tizanidine hcl level was high at presentation but not at a level where nephropathy is usually expected. Yet, uric acid increased with creatinine until administration of rasburicase. Whether this increase was enough to cause or contribute to the ARF is uncertain. Comparably, Larsen and Loghman-
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br Other candidate genes br The
2019-04-26
Other candidate genes The frequency of minor gene mutations in BrS As mentioned above, more than 10 genes have been reported to cause BrS. The proportions of BrS patients who are mutation carriers, however, are very small, except in the case of SCN5A. In a recent extensive mutation analysis of
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Hydrogen peroxide H O is
2019-04-25
Hydrogen peroxide (H2O2) is shown to readily promote EADs and triggered activity in isolated rat and rabbit ventricular myocytes by increasing both the L-type Ca channel (ICa-L) and late sodium currents (INa-L) [31–35]. However, this same stress fails to cause EADs in normal non-fibrotic cardiac tis
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In February a left neck infiltrating
2019-04-25
In February 2013, a left neck infiltrating purpuric lesion around a previous surgical scar (lymph node biopsy) with mild pain was noted. A subsequent skin biopsy revealed metastatic adenocarcinoma, compatible with ampulla of Vater primary, thereby confirming disease progression with skin metastasis.
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br Role of ICD treatment In patients
2019-04-24
Role of ICD treatment In patients with VT associated with various structural bet inhibitor diseases, ICD therapy is recommended even if the target VT is successfully ablated and no VT is inducible after catheter ablation [29]. This is because, in such patients, the same VT and/or new VT recurs du
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Although no GWAS results have been reported so
2019-04-24
Although no GWAS results have been reported so far from Asian populations, the candidate gene approach identified SNPs in 4q25 and 1q21 as being associated with AF in Asian populations [19,20]. Conflicting data are reported in terms of 16q22; it is associated with AF in Chinese Han [37], but not in
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br Discussion Over the past two decades the incidence of
2019-04-24
Discussion Over the past two decades, the incidence of second primary malignancy has progressively risen among cancer survivors and is an issue of increasingly greater concern in oncology. The increasing incidence may be due to the elevated rate of early cancer detection, improved cancer treatmen
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br Results Twenty seven bone lesions were analyzed
2019-04-24
Results Twenty-seven bone lesions were analyzed in 27 patients. Twelve of the patients were female and 15 were male. The mean age of the patients was 58 years with a range of 21–84 years. Ten lesions were determined to be malignant and 17 benign. Benign lesions of bone dropped in signal on out-of
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br Methods br Results br Discussion The results of
2019-04-24
Methods Results Discussion The results of this study demonstrate that (1) low-dose landiolol (0.5μgkg−1min−1) prevent heart rate elevation after AF ablation; (2) prophylactic administration of low-dose landiolol successfully prevented immediate AF recurrence within 3d after AF ablation with
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In addition to inducing IKs dysfunction through
2019-04-24
In addition to inducing IKs dysfunction through dominant-negative loss-of-function effects and defective channel trafficking, mutations in KCNQ1 suppress IKs channel function by reducing the channel affinity of interacting proteins [68,69]. Phosphatidylinositol-4,5-bisphosphate (PIP2) is a cofactor
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br Material and methods br Results A total of
2019-04-24
Material and methods Results A total of 4014 subjects were enrolled and registered during the initial recruitment nf-κb pathway from September 2013 through March 2015. In total, 167 subjects were excluded because of missing pivotal data such as height, body weight, or age (date of birth). Fina
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