• Introduction Pulmonary vein isolation PVI is an

  2019-05-09

  

  Introduction Pulmonary vein isolation (PVI) is an established strategy of paroxysmal atrial fibrillation (PAF) ablation [1–3]. Radiofrequency catheters have been the standard for AF ablation; however, PVI using balloon-based ablation has been increasingly adopted by electrophysiology laboratories a

• Maharaj K Bhan s accompanying Comment correctly

  2019-05-09

  

  Maharaj K Bhan\'s accompanying Comment correctly identifies that the main need is to obtain estimates on cause-specific mortality that are specific to each district. In particular, improved understanding is needed of how three causes, which account for 80% of neonatal deaths (birth asphyxia or traum

• Vollmer and colleagues distinctive multilevel modelling has

  2019-05-09

  

  Vollmer and colleagues\' distinctive multilevel modelling has potential weaknesses that warrant further investigation. The authors imply that tremendous statistical power is derived from the availability of Demographic and Health Survey data for about 460 000 children and their households. But becau

• Evidence of the efficacy of topiramate in PTC

  2019-05-09

  

  Evidence of the efficacy of topiramate in PTC has been reported in the literature [41,42]. The largest study, an open-label trial by Celebisoy and colleagues [41], demonstrated the non-inferiority of topiramate to acetazolamide in the management of idiopathic intracranial a01 in a population consist

• br is a bacterial infection causing

  2019-05-09

  

  is a bacterial infection causing necrotising lesions of skin and subcutaneous tissue. Widely known as Buruli ulcer, it is classified as a neglected tropical disease by WHO. If diagnosed and treated early, outcomes are good, but if left untreated it can progress to a severe disease resulting in hig

• The extraction of primary teeth has shown a significant upwa

  2019-05-09

  

  The extraction of primary teeth has shown a significant upward trend since 2011, and after 2012, these numbers showed a significant difference compared with 2006. One possible explanation for this buy abk was the high failure rate of upper anterior composite resin strip crowns placed over teeth aft

• br Discussion Rarely a breast cancer

  2019-05-09

  

  Discussion Rarely, a breast cancer patient has histologically proven breast cancer found outside the breast without a detectable primary breast tumor. Almost always the site of detected disease is an axillary lymph node. The incidence of axillary breast cancer with occult primary is relative low,

• br Epidemiology Electrophysiological BrS phenotypes occur pr

  2019-05-09

  

  Epidemiology Electrophysiological BrS phenotypes occur predominantly in young male adults (bcrp inhibitor rate, autonomic nervous system activity, some types of drugs, and a febrile state. Therefore, the true prevalence of BrS in the general population is difficult to estimate. However, the BrS p

• br Methods br Results The clinical genetic electrocardiograp

  2019-05-09

  

  Methods Results The clinical, genetic, electrocardiographic, and electrophysiological characteristics of the study patients are shown in Table 1. Eight of the 45 patients were symptomatic, having a history of syncope (n=3) or aborted SCD (n=5). The remaining 37 patients were asymptomatic, alth

• Introduction Ewing s sarcoma ES

  2019-05-09

  

  Introduction Ewing\'s sarcoma (ES) is a high-grade neoplasm representing the second most common primary bone malignancy in both children and adults. With a peak incidence at 15 years, this disease accounts for 2% of childhood cancers [1–3]. ES is defined as a bone tumor which may occur at any site

• br Materials and methods br Results br Discussion Utilizing

  2019-05-09

  

  Materials and methods Results Discussion Utilizing IHC, the majority of OS samples were positive for RANKL (68%), with RANKL staining detectable in OS tumor VCH-222 and tumor anaplastic cells. However, a wide range of RANKL expression within the OS component was observed and many samples h

• ghrelin receptor Introduction Osteosarcoma OS is the most

  2019-05-09

  

  Introduction Osteosarcoma (OS) is the most common type of bone tumor occurred in adolescents and children [1]. OS is highly malignant and accounts for about half of bone sarcomas with high potential of metastasis [2]. Treatment for OS is mainly depended on surgical operation, assisted with chemothe

• According to the labeling of dabigatran in Japan patients

  2019-05-09

  

  According to the labeling of dabigatran in Japan, patients to be considered for the prescription of the lower dose of 220mg/day are as follows: (1) aged ≥70 years, (2) with moderate renal impairment (ClCr 30–50mL/min), (3) concomitant use of a p-glycoprotein inhibitor, and (4) history of hemorrhage

• It is important to know whether pilsicainide can be

  2019-05-09

  

  It is important to know whether pilsicainide can be used as a therapeutic agent for LQT2 patients; and if so, we should determine the types of LQT2 mutation carriers to whom pilsicainide could be administered. As shown in Fig. 8, we examined the effects of pilsicainide on two mutant hERG proteins, G

• br Acknowledgments The authors would like to thank Sarah Mac

  2019-05-08

  

  Acknowledgments The authors would like to thank Sarah Mack for technical assistance with the histology and IHC. We would also like to acknowledge Dr. Gregory Dieudonne in the Department of Musculoskeletal Radiology, University of Rochester Medical Center for advice and assistance in manuscript wr

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