• In our study ES SCLC patients in

  2019-06-13

  

  In our study, ES-SCLC patients in the CIT group were on average older than those in the control group. However, the multivariate analysis showed that age had no effect on the prognosis of these patients. Therefore, age was no a confounding factor, although it has been reported that effector cell fun

• br Quantitative analysis The quantitative

  2019-06-13

  

  Quantitative analysis The quantitative analysis is based on modeling the concentration change of the contrast agent using pharmacokinetic modeling techniques. An initial conversion of SI to concentration values is needed. Concentration vs time curves are then fitted using a bi-compartmental PK mo

• br OPG RANK and RANKL contribute to the vicious

  2019-06-13

  

  OPG, RANK and RANKL contribute to the vicious cycle established between tumour bch and bone microenvironment: evidences for sarcomas and carcinomas RANK/RANKL axis is involved in the tumorigenic process RANK/RANKL axis is associated with the bone metastastic process, and as several arguments

• br Conclusions br Acknowledgements This

  2019-06-13

  

  Conclusions Acknowledgements This work was supported by Bloodwise, the International Myeloma Foundation and a Marie Curie Career Integration Grant from the European Union Seventh Framework Programme (FP7/2007-2013) under grant agreement n° [294160]. The osteoblast in normal bone physiology

• The presence of an inflammatory infiltrate

  2019-06-13

  

  The presence of an inflammatory infiltrate is associated with poor prognosis in a number of malignancies, including those with a predilection for metastasis to bone. CAFs are capable of promoting, and maintaining an inflammatory environment by recruiting immune cells; in particular monocyte/macropha

• A type saddle back type or

  2019-06-13

  

  A type 2 (“saddle-back type”) or type 3 ST-segment elevation cannot substitute for a type 1, unless converted to type 1 with fever or sodium drug challenge. A drug challenge–induced type 1 can be used to diagnose BrS only if accompanied by 1 of the criteria specified above. Type 2 is characterized b

• Vollmer and colleagues distinctive multilevel modelling has

  2019-06-13

  

  Vollmer and colleagues\' distinctive multilevel modelling has potential weaknesses that warrant further investigation. The authors imply that tremendous statistical power is derived from the availability of Demographic and Health Survey data for about 460 000 children and their households. But becau

• Climate change will have far reaching effects on how we

  2019-06-13

  

  Climate change will have far-reaching effects on how we build, organise, and manage health systems as complex institutions. Yet, to date, these challenges have largely been ignored by the research community. Despite substantial work by WHO on the interface between climate and health, two major confe

• br EL CONTEXTO DE LAS NEGOCIACIONES Y LA

  2019-06-13

  

  EL CONTEXTO DE LAS NEGOCIACIONES Y LA AGENDA BILATERAL El avance de Cuba en el fortalecimiento de sus vínculos con América Latina y el Caribe ha sido destacado. En marzo y junio de 2009, Costa Rica y El Salvador, respectivamente, restablecieron relaciones diplomáticas con la Isla, con ello, toda

• br El Movimiento Espa ol ha

  2019-06-13

  

  El Movimiento Español 1959, ha sido definido por Eduardo Mateo Gambarte como: “el último latido de los más jóvenes exiliados por incorporarse MDV3100 la lucha antifranquista”. Pese a su limitado número de participantes y su corto recorrido, representó un fenómeno destacable al estar encabezado por

• Two fundamental objections to the conclusion that mass dewor

  2019-06-12

  

  Two fundamental objections to the conclusion that mass deworming for helminths has no benefits and could therefore be abandoned have been repeatedly raised. First, the underlying studies might have been insufficient to detect benefits, because the follow-up for most studies was too short to detect h

• Patients were divided randomly into two

  2019-06-12

  

  Patients were divided randomly into two groups at the time of hCG administration. Patients in Group 1 (n = 38; 33.6%) underwent IUI 24 hours after hCG administration. Group 2 (n = 75; 66.4%) underwent IUI 36 hours after hCG administration. All patients were instructed to have intercourse when the do

• br Future potential cardiac examinations for

  2019-06-12

  

  Future potential cardiac examinations for long-duration spaceflights Currently available treatments for emergency cases in spaceflight Astronaut Crew Medical Officers (CMO) aboard the ISS receive 40–70h of medical training, including CPR training, within 18 months preceding their mission (Fig.

• br Clinical evidence to support that PES

  2019-06-12

  

  Clinical evidence to support that PES predicts cardiac events in BS Brugada et al. were the first to propose that inducibility of sustained ventricular arrhythmias with PES is useful to identify patients who are at high risk of SCD [3]. During follow-up of patients with spontaneous type 1 Brugada

• According to most published reports patients with Twiddler s

  2019-06-12

  

  According to most published reports, patients with Twiddler\'s syndrome are usually diagnosed due to some type of sudden device malfunction [1–4,6–15]. Early detection of this condition can also be achieved with a home monitoring system [8]. The case presented is a rare one in which Twiddler\'s synd

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