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br Discussion Case reports of successful
2019-06-25
Discussion Case reports of successful chemotherapy desensitizations have been described for platinum agents, taxanes, anthracyclines, rituximab [8], and cytarabine [9], but not specifically clofarabine. For older patients with relapsed AML that are not candidates to receive anthracycline therapy,
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Since antithrombotic therapy for patients with
2019-06-25
Since antithrombotic therapy for patients with AF is rapidly changing with the increasing use of dabigatran, rivaroxaban, and apixaban, some of the primary issues that will influence the future revision of various guidelines (HRS [Heart Rhythm Society], ESC [European Society of Cardiology], ACC [Ame
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br Quantitative analysis The quantitative analysis is based
2019-06-25
Quantitative analysis The quantitative analysis is based on modeling the concentration change of the contrast agent using pharmacokinetic modeling techniques. An initial conversion of SI to concentration values is needed. Concentration vs time curves are then fitted using a bi-compartmental PK mo
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Current treatment options for paroxysmal
2019-06-25
Current treatment options for paroxysmal supraventricular tachycardias include AV purinergic receptor blocking agents (verapamil, diltiazem, propranolol, and metoprolol), class IC anti-arrhythmic agents (propafenone and flecainide), and catheter ablation. The identification of frequent coexistence
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br Discussion Bone marrow fibrosis is known
2019-06-25
Discussion Bone marrow fibrosis is known to be associated with hematolymphoid malignancies such as acute leukemia, Hodgkin and non-Hodgkin lymphoma. Among the acute leukemias, marrow fibrosis is most often seen with acute megakaryoblastic leukemia. It is an uncommon finding in APL and till date o
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br Introduction Incidence of oral cancers accounts for of
2019-06-25
Introduction Incidence of oral cancers accounts for ∼3% of all malignancies. Oral squamous cell carcinoma (OSCC) accounts for >95% of all malignancies in the oral cavity, and it is the fifth leading cause of cancer death in the male population in Taiwan. OSCC is treated mainly with surgery. Post
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br Results and discussion In this study the np and
2019-06-24
Results and discussion In this study, the np9 and gag mRNA expression was established for 25 patients with CLL (Fig. 1). We found that the transcriptional activity of HERV-K np9 gene in CLL patients was higher than in PBMCs from healthy donors. The results revealed that 18 out of 25 CLL patients
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br Epidemiology Electrophysiological BrS phenotypes occur pr
2019-06-24
Epidemiology Electrophysiological BrS phenotypes occur predominantly in young male adults (by hedgehog signaling rate, autonomic nervous system activity, some types of drugs, and a febrile state. Therefore, the true prevalence of BrS in the general population is difficult to estimate. However, t
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In the s several hospital based surveys
2019-06-24
In the 1990s, several hospital-based surveys were reported. In a survey of AF among 2686 acute medical admissions to a district general hospital in Glasgow, UK [4], the prevalence of AF was 6.3%, with the predominant associated medical conditions being ischemic heart disease, hypertension, and valvu
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DALYs as a tool for measuring the burden of breast
2019-06-24
DALYs, as a tool for measuring the burden of breast cancer, is useful for public health and for burden of disease analyses. DALYs can add useful available information for monitoring services and conducting health-related economic analyses for cost-effective planning in the country. As noted earlier,
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Linezolid weight br Patients and methods br Results
2019-06-24
Patients and methods Results Discussion In the ZOTECT study, ZOL therapy was associated with significantly decreased P1NP and CTX levels within 1 month of initiating treatment (PLinezolid weight with data from a small trial in patients with newly diagnosed bone metastases from PC, BC, or lu
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In the phase AZURE trial women were randomly assigned
2019-06-24
In the phase 3 AZURE trial, 3360 women were randomly assigned to receive standard adjuvant systemic treatment alone (control group) or with 4mg intravenous zoledronic ABC294640 structure every 3–4 weeks for 6 doses, then every 3 months for 8 doses, followed by every 6 months for 5 doses, for a tota
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br Treatment and follow up
2019-06-24
Treatment and follow-up recommendations for patients receiving aromatase inhibitors Conclusions and future directions It is evident that, in addition to BMD, clinical risk factors can greatly influence fracture risk. In addition to morbidity and mortality, fractures are associated with high he
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Poor knowledge among caretakers of how
2019-06-24
Poor knowledge among caretakers of how to work with disability-related disorders could also be an issue. For example, poor knowledge of how to correctly position a child with severe cerebral palsy could lead to inadequate feeding; at worst, these efforts can cause aspiration and even death. Social a
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Is this perhaps a manifestation
2019-06-24
Is this perhaps a manifestation of the unequal distribution of growth, reflecting a pattern whereby income increases over the past two decades have benefited only the better-off? The evidence suggests that this is unlikely: across countries, Vollmer and colleagues report similar associations between
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